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Compound Detail

CHEMBL2369788

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CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)CCc1c[nH]c2ccccc12

Basic Information

ChEMBL ID CHEMBL2369788
Phase Preclinical
Structure Type MOL
InChI Key OLNJHAIPLFPWSY-CPPKSIGKSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

1019.2
MW (Da)

Drug Information

Molecule Type Unknown
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C53H70N12O9
MW 1019.22

Activity Summary

Ki 1 meas. best 8.34

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Lutropin-choriogonadotropic hormone receptor
CHEMBL2456
Ki 8.34 8.34 4.6 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
2552116 10.1021/jm00130a019 Lutropin-choriogonadotropic hormone receptor 2

Data from ChEMBL 36 via Core Engine