Compound Detail
CHEMBL2370114
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
COc1ccc(C[C@@H]2NC(=O)[C@H](CO)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)[C@@H]3CCCN3C(=O)CNC(=O)[C@@H]3CCN3C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC2=O)cc1
Basic Information
| ChEMBL ID | CHEMBL2370114 |
| Phase | Preclinical |
| Structure Type | BOTH |
| InChI Key | NCQVJGLKVJYHCR-BRLNAHGRSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
1280.5
MW (Da)
Drug Information
| Molecule Type | Protein |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.58
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.58 | 5.58 | 2630.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 2630.27 | nM | 5.58 | Displacement of [125I]-Tyr6, His5 from human LHRH1 receptor expressed in HEK 293... | 23127987 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23127987 | 10.1016/j.ejmech.2012.09.043 | Unchecked | 2 |
| 23127987 | 10.1016/j.ejmech.2012.09.043 | ADMET | 1 |
Data from ChEMBL 36 via Core Engine