Compound Detail
CHEMBL237120
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL237120 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LQWVHRDICKZHCX-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
418.9
MW (Da)
4.46
ALogP
4
HBA
0
HBD
58.4
PSA (Ų)
0.62
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.92
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Vasopressin V2 receptor CHEMBL1790 | IC50 | 5.92 | 5.92 | 1214.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Vasopressin V2 receptor | IC50 | = | 1214.0 | nM | 5.92 | Displacement of [3H]AVP from human vasopressin V2 receptor expressed in mouse LV... | 17855087 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17855087 | 10.1016/j.bmcl.2007.08.053 | Vasopressin V2 receptor | 1 |
| 17855087 | 10.1016/j.bmcl.2007.08.053 | Vasopressin V1a receptor | 1 |
| 17855087 | 10.1016/j.bmcl.2007.08.053 | Rattus norvegicus | 1 |
Data from ChEMBL 36 via Core Engine