Compound Detail
CHEMBL2371649
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CN(C(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](N)CCCN=C(N)N)[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O
Basic Information
| ChEMBL ID | CHEMBL2371649 |
| Phase | Preclinical |
| Structure Type | BOTH |
| InChI Key | WBBTXKGNCKTYFN-JMNYKWSOSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
1124.3
MW (Da)
Drug Information
| Molecule Type | Protein |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 9.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 9.0 | 8.24 | 1.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 1.0 | nM | 9.0 | Inhibitory activity against low affinity binding site of Bradykinin receptor in ... | 8632416 |
| Unchecked | IC50 | = | 33.0 | nM | 7.48 | Inhibitory activity against low affinity binding site of Bradykinin receptor in ... | 8632416 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8632416 | 10.1021/jm9301954 | Cavia porcellus | 2 |
| 8632416 | 10.1021/jm9301954 | Unchecked | 2 |
| 8632416 | 10.1021/jm9301954 | Rattus norvegicus | 1 |
Data from ChEMBL 36 via Core Engine