Compound Detail
CHEMBL2374432
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Basic Information
| ChEMBL ID | CHEMBL2374432 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PLDAMRBUPCEOQR-NBYAQTDISA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
295.3
MW (Da)
-1.40
ALogP
9
HBA
5
HBD
152.7
PSA (Ų)
0.45
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Nucleic Acid CHEMBL345 | EC50 | 4.0 | 4.0 | 100000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Nucleic Acid | EC50 | = | 100000.0 | nM | 4.0 | Inhibition of HCV RNA replication in a subgenomic bicistronic replicon assay in ... | 15456273 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15456273 | 10.1021/jm040068f | Nucleic Acid | 1 |
| 15456273 | 10.1021/jm040068f | NON-PROTEIN TARGET | 1 |
Data from ChEMBL 36 via Core Engine