Compound Detail
CHEMBL2381067
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL2381067 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WTMAGUQYKJOINO-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
315.4
MW (Da)
4.72
ALogP
2
HBA
1
HBD
38.3
PSA (Ų)
0.72
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.33
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Endothelial lipase CHEMBL2380190 | IC50 | 6.33 | 6.33 | 470.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Endothelial lipase | IC50 | = | 470.0 | nM | 6.33 | Inhibition of mouse EL expressed in HEK293 cells using PED-A1 as substrate by sp... | 23528297 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23528297 | 10.1016/j.bmcl.2013.02.113 | Endothelial lipase | 1 |
Data from ChEMBL 36 via Core Engine