Compound Detail
CHEMBL2386368
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL2386368 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UMRQJURSOGCUGX-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
404.5
MW (Da)
2.80
ALogP
4
HBA
1
HBD
80.7
PSA (Ų)
0.54
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 6.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Free fatty acid receptor 4 CHEMBL5339 | EC50 | 6.52 | 6.52 | 300.0 | 1 |
| Free fatty acid receptor 1 CHEMBL4422 | EC50 | 6.21 | 6.21 | 616.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Free fatty acid receptor 4 | EC50 | = | 300.0 | nM | 6.52 | Agonist activity at C-terminal yellow fluorescent protein-fused human FFA4 recep... | 23687558 |
| Free fatty acid receptor 1 | EC50 | = | 616.6 | nM | 6.21 | Agonist activity at human FFA1 receptor transfected in human 1321N1 cells by cal... | 23687558 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23687558 | 10.1021/ml4000673 | Free fatty acid receptor 4 | 2 |
| 23687558 | 10.1021/ml4000673 | Free fatty acid receptor 1 | 2 |
Data from ChEMBL 36 via Core Engine