Compound Detail
CHEMBL238939
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Basic Information
| ChEMBL ID | CHEMBL238939 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BWGFZDUSGNRJEF-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
432.4
MW (Da)
4.07
ALogP
6
HBA
2
HBD
77.4
PSA (Ų)
0.61
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.28
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Vascular endothelial growth factor receptor 1 CHEMBL1868 | IC50 | 5.28 | 5.28 | 5290.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Vascular endothelial growth factor receptor 1 | IC50 | = | 5290.0 | nM | 5.28 | Inhibition of VEGFR1 by HTRF assay | 17188873 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17188873 | 10.1016/j.bmcl.2006.11.087 | Vascular endothelial growth factor receptor 2 | 2 |
| 17188873 | 10.1016/j.bmcl.2006.11.087 | Vascular endothelial growth factor receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine