Compound Detail
CHEMBL23906
5-CHLOROINDOLE-2-CARBOXYLIC ACID Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL23906 |
| Name | 5-CHLOROINDOLE-2-CARBOXYLIC ACID |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FUQOTYRCMBZFOL-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
195.6
MW (Da)
2.52
ALogP
1
HBA
2
HBD
53.1
PSA (Ų)
0.73
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 2.46
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Coagulation factor VII/tissue factor CHEMBL2095194 | Ki | 2.46 | 2.46 | 3500000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Coagulation factor VII/tissue factor | Ki | = | 3500000.0 | nM | 2.46 | Inhibition of human soluble tissue factor/factor VIIa expressed in Origami B (DE... | 25764119 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1849994 | 10.1021/jm00108a007 | Glutamate NMDA receptor | 1 |
| 15115392 | 10.1021/jm0305117 | NS3 | 1 |
| 23571415 | 10.1124/mol.112.084152 | Solute carrier organic anion transporter family member 1B1 | 1 |
| 23571415 | 10.1124/mol.112.084152 | Solute carrier organic anion transporter family member 1B3 | 1 |
| 25764119 | 10.1021/jm501982k | Coagulation factor VII/tissue factor | 1 |
| 30343193 | 10.1016/j.ejmech.2018.10.027 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine