Compound Detail
CHEMBL2393341
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL2393341 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UZYGRPKEIPMAGS-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
217.3
MW (Da)
1.61
ALogP
4
HBA
2
HBD
60.2
PSA (Ų)
0.82
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 3.99
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fermitin family homolog 2 CHEMBL5465266 | IC50 | 3.99 | 3.99 | 103000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Fermitin family homolog 2 | IC50 | = | 103000.0 | nM | 3.99 | Inhibition of His6-tagged KIND2 (unknown origin) expressed in Escherichia coli B... | 38039505 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 38039505 | 10.1021/acs.jmedchem.3c00877 | Fermitin family homolog 2 | 2 |
| 23669191 | 10.1016/j.bmc.2013.04.040 | Unchecked | 1 |
| 23669191 | 10.1016/j.bmc.2013.04.040 | Ferriprotoporphyrin IX | 1 |
Data from ChEMBL 36 via Core Engine