Compound Detail
CHEMBL2407847
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL2407847 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VHKVOPUMZDYSAV-UHFFFAOYSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
343.8
MW (Da)
3.43
ALogP
5
HBA
2
HBD
67.2
PSA (Ų)
0.74
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 6.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Plasmodium falciparum CHEMBL364 | IC50 | 6.4 | 6.12 | 400.0 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Plasmodium falciparum | IC50 | = | 400.0 | nM | 6.4 | Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum 3D7 ... | 24900724 |
| Plasmodium falciparum | IC50 | = | 890.0 | nM | 6.05 | Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum K1 a... | 24900724 |
| Plasmodium falciparum | IC50 | = | 1240.0 | nM | 5.91 | Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum W2 a... | 24900724 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24900724 | 10.1021/ml4001084 | Plasmodium falciparum | 3 |
| 24900724 | 10.1021/ml4001084 | KB | 1 |
| 24900724 | 10.1021/ml4001084 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine