Compound Detail
CHEMBL241569
ERYCEBENIN E Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL241569 |
| Name | ERYCEBENIN E |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JCLYSCYJVYARSD-INIZCTEOSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
316.4
MW (Da)
3.48
ALogP
5
HBA
1
HBD
57.1
PSA (Ų)
0.94
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 5.54
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| U-937 CHEMBL612794 | IC50 | 5.54 | 5.1133 | 2900.0 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| U-937 | IC50 | = | 2900.0 | nM | 5.54 | Antiproliferative activity against human U937 cells after 72 hrs by WST-8 assay | 17158054 |
| U-937 | IC50 | = | 4300.0 | nM | 5.37 | Antiproliferative activity against human U937 cells after 48 hrs by WST-8 assay | 17158054 |
| U-937 | IC50 | = | 37000.0 | nM | 4.43 | Antiproliferative activity against human U937 cells after 24 hrs by WST-8 assay | 17158054 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17158054 | 10.1016/j.bmc.2006.09.024 | U-937 | 3 |
Data from ChEMBL 36 via Core Engine