Compound Detail
CHEMBL2435137
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Basic Information
| ChEMBL ID | CHEMBL2435137 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CYXDITGATVMCNR-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
360.5
MW (Da)
5.70
ALogP
3
HBA
0
HBD
25.2
PSA (Ų)
0.56
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.91
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glucagon receptor CHEMBL1985 | IC50 | 5.91 | 5.91 | 1230.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glucagon receptor | IC50 | = | 1230.27 | nM | 5.91 | Antagonist activity at human glucagon receptor | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1007/s00044-013-0801-3 | Glucagon receptor | 1 |
Data from ChEMBL 36 via Core Engine