Compound Detail
CHEMBL2441393
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Basic Information
| ChEMBL ID | CHEMBL2441393 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FTQHCTYSXMHPJD-UHFFFAOYSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
339.1
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 5.09
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| PBMC CHEMBL613107 | IC50 | 5.09 | 4.8667 | 8200.0 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| PBMC | IC50 | = | 8200.0 | nM | 5.09 | Antiinflammatory activity in human PBMC assessed as inhibition of LPS-induced IL... | 24075731 |
| PBMC | IC50 | = | 11000.0 | nM | 4.96 | Antiinflammatory activity in human PBMC assessed as inhibition of LPS-induced IL... | 24075731 |
| PBMC | IC50 | = | 28000.0 | nM | 4.55 | Antiinflammatory activity in human PBMC assessed as inhibition of LPS-induced TN... | 24075731 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24075731 | 10.1016/j.bmcl.2013.08.096 | PBMC | 3 |
Data from ChEMBL 36 via Core Engine