Compound Detail
CHEMBL2442201
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Basic Information
| ChEMBL ID | CHEMBL2442201 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UAEZPQXQAIYKCX-UHHYTMRFSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
1643.7
MW (Da)
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| ECV-304 CHEMBL614035 | IC50 | 5.05 | 4.865 | 9000.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| ECV-304 | IC50 | = | 9000.0 | nM | 5.05 | Cytotoxicity against human ECV304 cells after 72 hrs by MTT assay | 24084294 |
| ECV-304 | IC50 | = | 21000.0 | nM | 4.68 | Membrane toxicity against human ECV304 cells after 2 hrs by LDH release assay | 24084294 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24084294 | 10.1016/j.bmc.2013.09.008 | ECV-304 | 6 |
Data from ChEMBL 36 via Core Engine