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Compound Detail

CHEMBL2442215

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CC[N+](CC)(CCCCCC[N+](CC)(CC)CC/N=C1\C[C@H]2CC[C@]1(C)C2(C)C)CC/N=C1\C[C@H]2CC[C@]1(C)C2(C)C.[Br-].[Br-]

Basic Information

ChEMBL ID CHEMBL2442215
Phase Preclinical
Structure Type MOL
InChI Key FUGOHTFYMDYMSW-LDZUXMKSSA-L
Parent Compound CHEMBL3040682
Active Moiety CHEMBL3040682
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names

Molecular Properties

585.0
MW (Da)
8.83
ALogP
2
HBA
0
HBD
24.7
PSA (Ų)
0.12
QED
2
Ro5 Violations
17
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C38H72Br2N4
MW 744.83
Aromatic Rings 0
Heavy Atoms 42
NP-Likeness 0.43

Activity Summary

EC50 1 meas. best 4.09

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
NON-PROTEIN TARGET
CHEMBL3879801
EC50 4.09 4.09 81200.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
NON-PROTEIN TARGET EC50 = 81200.0 nM 4.09 Antiviral activity against Influenza virus A/California/07/09 (H1N1)pdm09 infect... 23993669

Literature References

Data from ChEMBL 36 via Core Engine