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Compound Detail

CHEMBL2442217

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CC[N+](CC)(CCCCCCCCC[N+](CC)(CC)CC/N=C1\C[C@H]2CC[C@]1(C)C2(C)C)CC/N=C1\C[C@H]2CC[C@]1(C)C2(C)C.[Br-].[Br-]

Basic Information

ChEMBL ID CHEMBL2442217
Phase Preclinical
Structure Type MOL
InChI Key BTKPUZLYYPSXJZ-AKKIWZJDSA-L
Parent Compound CHEMBL3040719
Active Moiety CHEMBL3040719
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names

Molecular Properties

627.1
MW (Da)
10.00
ALogP
2
HBA
0
HBD
24.7
PSA (Ų)
0.09
QED
2
Ro5 Violations
20
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C41H78Br2N4
MW 786.91
Aromatic Rings 0
Heavy Atoms 45
NP-Likeness 0.40

Activity Summary

EC50 1 meas. best 5.16

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
NON-PROTEIN TARGET
CHEMBL3879801
EC50 5.16 5.16 6900.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
NON-PROTEIN TARGET EC50 = 6900.0 nM 5.16 Antiviral activity against Influenza virus A/California/07/09 (H1N1)pdm09 infect... 23993669

Literature References

Data from ChEMBL 36 via Core Engine