Compound Detail
CHEMBL2443087
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL2443087 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MIAPWXITKNBFGI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
381.9
MW (Da)
4.60
ALogP
3
HBA
1
HBD
65.4
PSA (Ų)
0.78
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.26
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Transient receptor potential cation channel subfamily M member 8 CHEMBL1075319 | IC50 | 6.26 | 6.26 | 543.7 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Transient receptor potential cation channel subfamily M member 8 | IC50 | = | 543.7 | nM | 6.26 | Antagonist activity at human TRPM8 expressed in CHO cells assessed as inhibition... | 24055075 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24055075 | 10.1016/j.bmc.2013.08.031 | Transient receptor potential cation channel subfamily M member 8 | 1 |
Data from ChEMBL 36 via Core Engine