Compound Detail
CHEMBL252925
GAMMA-FAGARINE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL252925 |
| Name | GAMMA-FAGARINE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KFBCTNNQFGONHB-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
10
Publications
0
Known Names
Molecular Properties
229.2
MW (Da)
3.00
ALogP
4
HBA
0
HBD
44.5
PSA (Ų)
0.68
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.5
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| NON-PROTEIN TARGET CHEMBL3879801 | IC50 | 4.5 | 4.5 | 31310.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| NON-PROTEIN TARGET | IC50 | = | 31310.0 | nM | 4.5 | Antiinflammatory activity in human neutrophils assessed as inhibition of formyl-... | 18211005 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15387647 | 10.1021/np0400611 | Unchecked | 4 |
| 15387647 | 10.1021/np0400611 | Raji | 4 |
| 18211005 | 10.1021/np070594k | NON-PROTEIN TARGET | 2 |
| 19128011 | 10.1021/np800689b | NON-PROTEIN TARGET | 2 |
| - | 10.1007/s00044-011-9581-9 | Acetylcholinesterase | 2 |
| 17822293 | 10.1021/np070186g | Neutrophil | 1 |
| 18564877 | 10.1021/np700719e | Mycobacterium tuberculosis | 1 |
| 22093759 | 10.1016/j.ejmech.2011.10.047 | HepG2 | 1 |
| 33609889 | 10.1016/j.ejmech.2021.113220 | Human immunodeficiency virus 1 | 1 |
| 37421889 | 10.1016/j.ejmech.2023.115609 | Leishmania major | 1 |
Data from ChEMBL 36 via Core Engine