Compound Detail
CHEMBL255690
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Basic Information
| ChEMBL ID | CHEMBL255690 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SFDSXIZFOOBDMC-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
511.6
MW (Da)
4.05
ALogP
10
HBA
2
HBD
123.7
PSA (Ų)
0.27
QED
1
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.89
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Apoptosis regulator Bcl-2 CHEMBL4860 | Ki | 5.89 | 5.89 | 1288.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Apoptosis regulator Bcl-2 | Ki | = | 1288.25 | nM | 5.89 | Binding affinity to BCL2 | 18040043 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18040043 | 10.1073/pnas.0709443104 | Apoptosis regulator Bcl-2 | 1 |
Data from ChEMBL 36 via Core Engine