Compound Detail
CHEMBL256862
IROMYCIN MO Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL256862 |
| Name | IROMYCIN MO |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MIXQIMNQZANDMA-ACCUITESSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
292.4
MW (Da)
4.68
ALogP
3
HBA
1
HBD
50.4
PSA (Ų)
0.56
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.07
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mitochondrial complex I; NADH oxidoreductase CHEMBL614865 | IC50 | 5.07 | 5.07 | 8550.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mitochondrial complex I; NADH oxidoreductase | IC50 | = | 8550.0 | nM | 5.07 | Inhibition of NADH-ubiquinone oxidoreductase assessed as NADH oxidase activity i... | 18054490 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18054490 | 10.1016/j.bmc.2007.11.023 | Mitochondrial complex I; NADH oxidoreductase | 1 |
Data from ChEMBL 36 via Core Engine