Compound Detail
CHEMBL258082
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Basic Information
| ChEMBL ID | CHEMBL258082 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XGFXEFFLCCASGV-OWOJBTEDSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
374.4
MW (Da)
5.60
ALogP
4
HBA
1
HBD
61.3
PSA (Ų)
0.35
QED
1
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 9.33
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | Ki | 9.33 | 9.33 | 0.5 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | Ki | = | 0.47 | nM | 9.33 | Displacement of [125I]TZDM from beta amyloid protein 42 | 18226893 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18226893 | 10.1016/j.bmcl.2007.10.004 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine