Compound Detail
CHEMBL260202
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
C#C[C@]1(O)CC[C@H]2[C@@H]3CC[C@H]4CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C
Basic Information
| ChEMBL ID | CHEMBL260202 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PVHMKHVQVIUQIP-JJFNZWTKSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
314.5
MW (Da)
3.96
ALogP
2
HBA
1
HBD
37.3
PSA (Ų)
0.69
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 9.74
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Sex hormone-binding globulin CHEMBL3305 | Kd | 9.74 | 9.74 | 0.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Sex hormone-binding globulin | Kd | = | 0.182 | nM | 9.74 | Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding gl... | 18330978 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2002446 | 10.1021/jm00107a021 | Androgen receptor | 2 |
| 18330978 | 10.1021/jm7011485 | Sex hormone-binding globulin | 1 |
Data from ChEMBL 36 via Core Engine