Sex hormone-binding globulin · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P04278. Use UniProt P04278 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P04278 as the stable identity anchor, then attach disease evidence before program review.
Sex hormone-binding globulin
Review this target as Sex hormone-binding globulin, mapped to UniProt P04278. Sequence length is 402 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Sex hormone-binding globulin as ChEMBL target CHEMBL3305, mapped to UniProt P04278. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Sex hormone-binding globulin is the right protein anchor across sources, using UniProt P04278 as the stable mapping.
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| Preferred Name | Sex hormone-binding globulin |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P04278 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sex hormone-binding globulin |
| UniProt Accession | P04278 |
| Component Type | Protein |
| Sequence Length | 402 aa |
Sex hormone-binding globulin
Review this target as Sex hormone-binding globulin, mapped to UniProt P04278. Sequence length is 402 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL260202 | 9.74 | Kd | 0.182 | Preclinical |
| CHEMBL27769 | 9.74 | Kd | 0.182 | Clinical |
| CHEMBL258918 | 9.6 | Kd | 0.2512 | Clinical |
| CHEMBL259126 | 9.54 | Kd | 0.2884 | Preclinical |
| CHEMBL411053 | 9.38 | Kd | 0.4169 | Preclinical |
| CHEMBL265926 | 9.32 | Kd | 0.4786 | Preclinical |
| CHEMBL265925 | 9.31 | Kd | 0.4898 | Preclinical |
| CHEMBL386630 | 9.2 | Kd | 0.631 | Approved |
| CHEMBL440283 | 9.17 | Kd | 0.6761 | Preclinical |
| CHEMBL260660 | 9.12 | Kd | 0.7586 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 26 | 100 | 7.4 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 7 | 1 | 7.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 1 | 8.4 |