Compound Detail
CHEMBL262794
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Basic Information
| ChEMBL ID | CHEMBL262794 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AMECFCFFHHGFQV-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
353.4
MW (Da)
2.54
ALogP
6
HBA
0
HBD
45.5
PSA (Ų)
0.79
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.64
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2A CHEMBL322 | Ki | 5.64 | 5.64 | 2300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2A | Ki | = | 2300.0 | nM | 5.64 | In vitro binding affinity towards 5-hydroxytryptamine 2A receptor in rat tissue ... | 14695828 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 14695828 | 10.1021/jm0309811 | 5-hydroxytryptamine receptor 2A | 1 |
| 14695828 | 10.1021/jm0309811 | D(1A) dopamine receptor | 1 |
| 14695828 | 10.1021/jm0309811 | D(2) dopamine receptor | 1 |
| 14695828 | 10.1021/jm0309811 | D(3) dopamine receptor | 1 |
| 14695828 | 10.1021/jm0309811 | Dopamine D2 receptor and serotonin 2a receptor | 1 |
| 14695828 | 10.1021/jm0309811 | ADMET | 1 |
Data from ChEMBL 36 via Core Engine