Compound Detail
CHEMBL263590
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NCCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]1CNC(=O)C[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccc(O)cc2)NCc2ccccc2)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1)C(N)=O
Basic Information
| ChEMBL ID | CHEMBL263590 |
| Phase | Preclinical |
| Structure Type | BOTH |
| InChI Key | GOFBLFCMMMVTPI-VIBGGCSXSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
1408.6
MW (Da)
Drug Information
| Molecule Type | Protein |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 7.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | Ki | 7.52 | 6.375 | 30.3 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | Ki | = | 30.3 | nM | 7.52 | Inhibition of [3H]diprenorphine binding to kappa opioid receptor expressed in CH... | 15999987 |
| Unchecked | Ki | = | 5880.0 | nM | 5.23 | Inhibition of [3H]DAMGO ([D-Ala2,NMePhe4,glyol]-enkephalin) binding to mu opioid... | 15999987 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15999987 | 10.1021/jm050105i | Unchecked | 5 |
Data from ChEMBL 36 via Core Engine