Compound Detail
CHEMBL26364
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Basic Information
| ChEMBL ID | CHEMBL26364 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZJDARMHFLVJVAY-BQBZGAKWSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
248.3
MW (Da)
0.32
ALogP
7
HBA
3
HBD
115.9
PSA (Ų)
0.70
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 4.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| CCRF-CEM CHEMBL382 | IC50 | 4.05 | 4.05 | 90000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| CCRF-CEM | IC50 | = | 90000.0 | nM | 4.05 | Antitumor activity was evaluated against CEM cell line | 9871764 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9871764 | 10.1016/s0960-894x(98)00216-9 | L1210 | 1 |
| 9871764 | 10.1016/s0960-894x(98)00216-9 | MOLT-4 | 1 |
| 9871764 | 10.1016/s0960-894x(98)00216-9 | CCRF-CEM | 1 |
| 9871764 | 10.1016/s0960-894x(98)00216-9 | Human alphaherpesvirus 3 | 1 |
Data from ChEMBL 36 via Core Engine