Compound Detail
CHEMBL26440
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Basic Information
| ChEMBL ID | CHEMBL26440 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UZJUOSCDDMIVDO-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
7
Publications
0
Known Names
Molecular Properties
358.5
MW (Da)
4.81
ALogP
5
HBA
0
HBD
61.8
PSA (Ų)
0.28
QED
0
Ro5 Violations
17
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Protein kinase C (PKC) CHEMBL2094266 | IC50 | 4.0 | 4.0 | 100000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Protein kinase C (PKC) | IC50 | = | 100000.0 | nM | 4.0 | Inhibition of protein kinase C | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 22738638 | 10.1016/j.bmcl.2012.05.101 | Cannabinoid receptor 2 | 2 |
| - | 10.1016/S0960-894X(01)80433-9 | Protein kinase C (PKC) | 1 |
| - | 10.1016/S0960-894X(01)80433-9 | MR4 | 1 |
| - | 10.1016/S0960-894X(01)80433-9 | HT-29 | 1 |
| 22738638 | 10.1016/j.bmcl.2012.05.101 | Cannabinoid receptor 1 | 1 |
| 22738638 | 10.1016/j.bmcl.2012.05.101 | Monoglyceride lipase | 1 |
| 22738638 | 10.1016/j.bmcl.2012.05.101 | Fatty-acid amide hydrolase 1 | 1 |
Data from ChEMBL 36 via Core Engine