Compound Detail
CHEMBL265044
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
COC(=O)[C@@]12OC[C@]34[C@H]([C@@H](O)[C@@H]1O)[C@@]1(C)CC(=O)C(OC(=O)C(N)C(C)C)=C(C)[C@@H]1C[C@H]3OC(=O)[C@H](OC(=O)C(N)C(C)C)[C@@H]24
Basic Information
| ChEMBL ID | CHEMBL265044 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FORPMKOZGDEADL-JQUYLGCASA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
636.7
MW (Da)
-0.50
ALogP
14
HBA
4
HBD
224.0
PSA (Ų)
0.20
QED
2
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.24
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Plasmodium falciparum CHEMBL364 | EC50 | 6.24 | 6.24 | 570.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Plasmodium falciparum | EC50 | = | 570.0 | nM | 6.24 | Anti-malarial activity as growth inhibition of chloroquine-resistant Plasmodium ... | 9871598 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9871598 | 10.1016/s0960-894x(98)00045-6 | FM3A | 3 |
| 9871598 | 10.1016/s0960-894x(98)00045-6 | Plasmodium falciparum | 1 |
Data from ChEMBL 36 via Core Engine