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Compound Detail

CHEMBL265592

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CN(CCCCCCCCN(C)C(=O)CCCCCN(CC(=O)N1c2ccccc2C(=O)Nc2cccnc21)CC(=O)N1c2ccccc2C(=O)Nc2cccnc21)C(=O)CCCCCN(CC(=O)N1c2ccccc2C(=O)Nc2cccnc21)CC(=O)N1c2ccccc2C(=O)Nc2cccnc21

Basic Information

ChEMBL ID CHEMBL265592
Phase Preclinical
Structure Type MOL
InChI Key IHNBGTXJACQBDT-UHFFFAOYSA-N
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

1403.6
MW (Da)

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C78H82N16O10
MW 1403.62

Activity Summary

Kd 2 meas. best 7.75

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Muscarinic acetylcholine receptor M2
CHEMBL211
Kd 7.75 7.75 17.8 1
Muscarinic acetylcholine receptor M3
CHEMBL5498
Kd 5.67 5.67 2138.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
9767650 10.1021/jm981038d Muscarinic acetylcholine receptor M2 1
9767650 10.1021/jm981038d Muscarinic acetylcholine receptor M3 1

Data from ChEMBL 36 via Core Engine