Compound Detail
CHEMBL266053
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Basic Information
| ChEMBL ID | CHEMBL266053 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AJJARDBQFUEYGL-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
270.3
MW (Da)
3.34
ALogP
3
HBA
1
HBD
38.7
PSA (Ų)
0.85
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 7.24
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Homo sapiens CHEMBL372 | IC50 | 7.24 | 7.24 | 57.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 7.24 | 7.24 | 57.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 57.0 | nM | 7.24 | Inhibitory activity against Leukotriene B4 receptor in human PMN | 1313879 |
| Homo sapiens | IC50 | = | 57.0 | nM | 7.24 | Inhibitory activity against Leukotriene (LTB4) biosynthesis in isolated human po... | 2709371 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1313879 | 10.1021/jm00085a019 | Unchecked | 1 |
| 2709371 | 10.1021/jm00125a014 | Homo sapiens | 1 |
| 2709371 | 10.1021/jm00125a014 | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine