Compound Detail
CHEMBL268409
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CC(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](C(N)=O)C(c1ccccc1)c1ccccc1)[C@@H](C)O)C(C)C
Basic Information
| ChEMBL ID | CHEMBL268409 |
| Phase | Preclinical |
| Structure Type | BOTH |
| InChI Key | VERGKLFADWMPPI-KZWPSOAPSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
1991.3
MW (Da)
Drug Information
| Molecule Type | Protein |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.9
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Neuropeptide Y receptor type 1 CHEMBL4777 | IC50 | 5.9 | 5.9 | 1248.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Neuropeptide Y receptor type 1 | IC50 | = | 1248.0 | nM | 5.9 | Affinity against Neuropeptide Y receptor Y1 in SK-N-MC cell line | 10978189 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10978189 | 10.1021/jm000052z | Neuropeptide Y receptor type 2 | 2 |
| 10978189 | 10.1021/jm000052z | Neuropeptide Y receptor type 1 | 1 |
Data from ChEMBL 36 via Core Engine