Compound Detail
CHEMBL269644
ACETANILIDE 💊 Approved Drug
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
💊 Approved Drug
Basic Information
| ChEMBL ID | CHEMBL269644 |
| Name | ACETANILIDE |
| Phase | Approved |
| Structure Type | MOL |
| InChI Key | FZERHIULMFGESH-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
1
PK Parameters
20
Publications
9
Known Names
Molecular Properties
135.2
MW (Da)
1.65
ALogP
1
HBA
1
HBD
29.1
PSA (Ų)
0.62
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Withdrawn |
| Chirality | Achiral |
Drug Warnings
Withdrawn
hematological toxicity
Aplastic anaemia
Activity Summary
Ki 1 meas. best 9.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Nicotinate phosphoribosyltransferase CHEMBL4523354 | Ki | 9.0 | 9.0 | 1.0 | 1 |
Pharmacokinetic Data
| Parameter | Value | Units | Species |
|---|---|---|---|
| T1/2 | 0.7333 | hr | - |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Nicotinate phosphoribosyltransferase | Ki | = | 1.0 | nM | 9.0 | Inhibition of NAPRT (unknown origin) | - |
Literature References
Data from ChEMBL 36 via Core Engine