Compound Detail
CHEMBL270201
IROMYCIN AM Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL270201 |
| Name | IROMYCIN AM |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CXEJJNIHIKGTCH-VBONDNGNSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
317.5
MW (Da)
4.74
ALogP
2
HBA
1
HBD
42.1
PSA (Ų)
0.70
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.55
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mitochondrial complex I; NADH oxidoreductase CHEMBL614865 | IC50 | 5.55 | 5.55 | 2800.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mitochondrial complex I; NADH oxidoreductase | IC50 | = | 2800.0 | nM | 5.55 | Inhibition of NADH-ubiquinone oxidoreductase assessed as NADH oxidase activity i... | 18054490 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18054490 | 10.1016/j.bmc.2007.11.023 | Mitochondrial complex I; NADH oxidoreductase | 1 |
Data from ChEMBL 36 via Core Engine