Compound Detail
CHEMBL271026
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL271026 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BLVJRSYXUQVYGU-PRHRJOMZSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
275.4
MW (Da)
2.00
ALogP
3
HBA
2
HBD
60.8
PSA (Ų)
0.87
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.01
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mu-type opioid receptor CHEMBL2858 | EC50 | 5.01 | 5.01 | 9790.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mu-type opioid receptor | EC50 | = | 9790.0 | nM | 5.01 | Agonist activity at mu opioid receptor in Swiss mouse vas deferens assessed as i... | 17962026 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17962026 | 10.1016/j.bmc.2007.10.030 | Mus musculus | 4 |
| 17962026 | 10.1016/j.bmc.2007.10.030 | Unchecked | 2 |
| 17962026 | 10.1016/j.bmc.2007.10.030 | Mu-type opioid receptor | 1 |
Data from ChEMBL 36 via Core Engine