Compound Detail
CHEMBL272125
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Basic Information
| ChEMBL ID | CHEMBL272125 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FJAKKZSOEKERPY-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
346.4
MW (Da)
2.44
ALogP
5
HBA
1
HBD
83.6
PSA (Ų)
0.62
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.25
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Aurora kinase A CHEMBL4722 | IC50 | 6.25 | 6.25 | 560.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Aurora kinase A | IC50 | = | 560.0 | nM | 6.25 | Inhibition of Aurora A kinase (unknown origin) | 28918096 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 28918096 | 10.1016/j.ejmech.2017.08.045 | Aurora kinase A | 1 |
Data from ChEMBL 36 via Core Engine