Compound Detail
CHEMBL272435
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL272435 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NKEZFJKNNXIXRQ-ZZXKWVIFSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
276.1
MW (Da)
0.54
ALogP
5
HBA
4
HBD
133.5
PSA (Ų)
0.30
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 9.04
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | EC50 | 9.04 | 9.04 | 0.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | EC50 | = | 0.91 | nM | 9.04 | Agonist activity at human Vgamma9Vdelta2 receptor expressed in T cells assessed ... | 18303828 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18303828 | 10.1021/jm701101g | No relevant target | 5 |
| 18303828 | 10.1021/jm701101g | NON-PROTEIN TARGET | 4 |
| 18303828 | 10.1021/jm701101g | Unchecked | 1 |
| 18303828 | 10.1021/jm701101g | Rattus norvegicus | 1 |
Data from ChEMBL 36 via Core Engine