Compound Detail
CHEMBL27445
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Basic Information
| ChEMBL ID | CHEMBL27445 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UDLQBJXBRLQCHJ-CIUDSAMLSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
261.3
MW (Da)
-0.12
ALogP
7
HBA
3
HBD
110.1
PSA (Ų)
0.65
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.89
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| HepG2 CHEMBL395 | EC50 | 6.89 | 6.89 | 128.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| HepG2 | EC50 | = | 128.0 | nM | 6.89 | Tested for the effective concentration required to inhibit HBV in HepG2.2.15 hum... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(96)00594-X | HepG2 | 1 |
Data from ChEMBL 36 via Core Engine