Compound Detail
CHEMBL275976
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL275976 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FLNCALGJHBDOCD-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
314.4
MW (Da)
4.00
ALogP
4
HBA
0
HBD
36.9
PSA (Ų)
0.77
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.57
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Tubulin CHEMBL2094134 | IC50 | 5.57 | 5.57 | 2700.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Tubulin | IC50 | = | 2700.0 | nM | 5.57 | Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM... | 1552500 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1552500 | 10.1021/jm00084a011 | Tubulin | 3 |
Data from ChEMBL 36 via Core Engine