Compound Detail
CHEMBL276057
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Basic Information
| ChEMBL ID | CHEMBL276057 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CFMZSMGAMPBRBE-UHFFFAOYSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
10
Publications
0
Known Names
Molecular Properties
163.1
MW (Da)
0.67
ALogP
3
HBA
1
HBD
57.6
PSA (Ų)
0.45
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 4.84
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 4.84 | 4.82 | 14300.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 14300.0 | nM | 4.84 | Inhibition of Influenza A (A/California/04/2009) (H1N1) clinical isolate N-termi... | 30351002 |
| Unchecked | IC50 | = | 15848.93 | nM | 4.8 | Inhibition of Influenza A (A/California/04/2009) (H1N1) clinical isolate N-termi... | 30351002 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1992141 | 10.1021/jm00105a059 | Gallus gallus | 13 |
| 1992141 | 10.1021/jm00105a059 | ADMET | 2 |
| 30351002 | 10.1021/acs.jmedchem.8b01363 | Unchecked | 2 |
| 1992141 | 10.1021/jm00105a059 | Unchecked | 1 |
| 12646026 | 10.1021/jm020334u | Polymerase acidic protein | 1 |
| 19112024 | 10.1016/j.bmc.2008.11.075 | unidentified influenza virus | 1 |
| - | 10.1039/C5MD00439J | Polymerase acidic protein | 1 |
| 35450365 | 10.1021/acsmedchemlett.1c00721 | SW480 | 1 |
| 35450365 | 10.1021/acsmedchemlett.1c00721 | HCT-116 | 1 |
| 35450365 | 10.1021/acsmedchemlett.1c00721 | CCD-841CoN | 1 |
Data from ChEMBL 36 via Core Engine