Compound Detail
CHEMBL277382
PRODIPINE 🧪 Phase II
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🧪 Phase II
Basic Information
| ChEMBL ID | CHEMBL277382 |
| Name | PRODIPINE |
| Phase | Phase II |
| Structure Type | MOL |
| InChI Key | CFOOTBBXHJHHMT-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
2
Known Names
Molecular Properties
279.4
MW (Da)
4.48
ALogP
1
HBA
0
HBD
3.2
PSA (Ų)
0.80
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Achiral |
Activity Summary
Ki 1 meas. best 8.32
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cytochrome P450 2D6 CHEMBL289 | Ki | 8.32 | 8.32 | 4.8 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cytochrome P450 2D6 | Ki | = | 4.8 | nM | 8.32 | Inhibitory constant for cytochrome P450 2D6 | 8487254 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8487254 | 10.1021/jm00061a004 | Cytochrome P450 2D6 | 1 |
Data from ChEMBL 36 via Core Engine