Compound Detail
CHEMBL277545
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Basic Information
| ChEMBL ID | CHEMBL277545 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XMVIFVXBZMTDNR-MRXNPFEDSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
567.2
MW (Da)
3.27
ALogP
5
HBA
2
HBD
81.8
PSA (Ų)
0.40
QED
1
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate NMDA receptor CHEMBL1907608 | IC50 | 4.0 | 4.0 | 100000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate NMDA receptor | IC50 | = | 100000.0 | nM | 4.0 | Ability to displace [3H]L-689560 from NMDA receptor glycine site in rat brain me... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/0960-894X(96)00187-4 | Glutamate NMDA receptor | 1 |
Data from ChEMBL 36 via Core Engine