Compound Detail
CHEMBL277814
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Basic Information
| ChEMBL ID | CHEMBL277814 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VAUYHJTYTYEXGI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
450.5
MW (Da)
3.38
ALogP
7
HBA
2
HBD
101.9
PSA (Ų)
0.57
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.26
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Oryctolagus cuniculus CHEMBL374 | IC50 | 7.26 | 7.26 | 55.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Oryctolagus cuniculus | IC50 | = | 55.0 | nM | 7.26 | In vitro antiplatelet activity against arachidonic acid induced malondialdehyde ... | 8164261 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8164261 | 10.1021/jm00034a017 | Cavia porcellus | 4 |
| 8164261 | 10.1021/jm00034a017 | Oryctolagus cuniculus | 1 |
| 8164261 | 10.1021/jm00034a017 | Rattus norvegicus | 1 |
Data from ChEMBL 36 via Core Engine