Compound Detail
CHEMBL278483
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL278483 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XLOXYTHGLZKJKP-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
368.5
MW (Da)
4.06
ALogP
5
HBA
3
HBD
79.3
PSA (Ų)
0.47
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.21
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Oryctolagus cuniculus CHEMBL374 | IC50 | 7.21 | 7.21 | 62.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Oryctolagus cuniculus | IC50 | = | 62.0 | nM | 7.21 | In vitro antiplatelet activity against arachidonic acid induced malondialdehyde ... | 8164261 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8164261 | 10.1021/jm00034a017 | Cavia porcellus | 4 |
| 8164261 | 10.1021/jm00034a017 | Oryctolagus cuniculus | 1 |
| 8164261 | 10.1021/jm00034a017 | Rattus norvegicus | 1 |
Data from ChEMBL 36 via Core Engine