Compound Detail
CHEMBL279954
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Basic Information
| ChEMBL ID | CHEMBL279954 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JIOAMLXSOPAXFI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
395.9
MW (Da)
6.69
ALogP
3
HBA
0
HBD
30.7
PSA (Ų)
0.48
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 8.27
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Corticotropin releasing factor receptor CHEMBL2111360 | Ki | 8.27 | 8.27 | 5.4 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Corticotropin releasing factor receptor | Ki | = | 5.4 | nM | 8.27 | In vitro binding affinity against Corticotropin releasing factor receptor in rat... | 12467632 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 12467632 | 10.1016/s0960-894x(02)00834-x | Corticotropin releasing factor receptor | 1 |
Data from ChEMBL 36 via Core Engine