Compound Detail
CHEMBL280179
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Basic Information
| ChEMBL ID | CHEMBL280179 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AHPRJNNEROVFTO-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
252.7
MW (Da)
1.55
ALogP
2
HBA
3
HBD
96.2
PSA (Ų)
0.77
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.93
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate NMDA receptor CHEMBL1907608 | Ki | 5.93 | 5.93 | 1180.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate NMDA receptor | Ki | = | 1180.0 | nM | 5.93 | Inhibition of strychnine-insensitive [3H]glycine binding to the N-methyl-D-aspar... | 1849994 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1849994 | 10.1021/jm00108a007 | Glutamate NMDA receptor | 1 |
Data from ChEMBL 36 via Core Engine