Compound Detail
CHEMBL282212
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Basic Information
| ChEMBL ID | CHEMBL282212 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GUHHCAVJLIYCJR-MQWKRIRWSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
216.3
MW (Da)
0.12
ALogP
4
HBA
3
HBD
106.4
PSA (Ų)
0.50
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Aminopeptidase B CHEMBL2452 | Ki | 5.7 | 5.7 | 2000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Aminopeptidase B | Ki | = | 2000.0 | nM | 5.7 | Competitive inhibition of aminopeptidase B or arginyl aminopeptidase purified fr... | 2566685 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2566685 | 10.1021/jm00126a039 | Leucyl-cystinyl aminopeptidase | 2 |
| 2566685 | 10.1021/jm00126a039 | Aminopeptidase B | 1 |
Data from ChEMBL 36 via Core Engine