Compound Detail
CHEMBL285556
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Basic Information
| ChEMBL ID | CHEMBL285556 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GXWHNNAJEOYVNF-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
433.6
MW (Da)
3.86
ALogP
5
HBA
2
HBD
79.9
PSA (Ų)
0.52
QED
0
Ro5 Violations
11
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 7.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Histamine H2 receptor CHEMBL4654 | Kd | 7.8 | 7.8 | 15.8 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Histamine H2 receptor | Kd | = | 15.85 | nM | 7.8 | Antagonistic activity by inhibition histamine H2 receptor from rats. | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(96)00249-1 | Histamine H2 receptor | 1 |
Data from ChEMBL 36 via Core Engine