Compound Detail
CHEMBL293584
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Basic Information
| ChEMBL ID | CHEMBL293584 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CDYLNUVNFDZTEB-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
212.2
MW (Da)
1.84
ALogP
4
HBA
2
HBD
88.0
PSA (Ų)
0.51
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Epidermal growth factor receptor CHEMBL203 | IC50 | 6.3 | 6.3 | 500.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Epidermal growth factor receptor | IC50 | = | 500.0 | nM | 6.3 | Inhibition of polyGAT phosphorylation | 1676428 |
| Epidermal growth factor receptor | IC50 | = | 500.0 | nM | 6.3 | Inhibition of EGFR | 1479375 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1676428 | 10.1021/jm00110a022 | Epidermal growth factor receptor | 2 |
| 1676428 | 10.1021/jm00110a022 | NIH3T3 | 1 |
| 1479375 | 10.1021/np50089a001 | Epidermal growth factor receptor | 1 |
Data from ChEMBL 36 via Core Engine