Compound Detail
CHEMBL293698
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Basic Information
| ChEMBL ID | CHEMBL293698 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YLMAQFUMCKHRAF-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
154.3
MW (Da)
0.92
ALogP
2
HBA
2
HBD
24.1
PSA (Ų)
0.42
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Peroxisomal N(1)-acetyl-spermine/spermidine oxidase CHEMBL2105 | Ki | 6.52 | 6.52 | 300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Peroxisomal N(1)-acetyl-spermine/spermidine oxidase | Ki | = | 300.0 | nM | 6.52 | Inhibitory activity measured as apparent dissociation constant against Polyamine... | 3965702 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 3965702 | 10.1021/jm00379a001 | Peroxisomal N(1)-acetyl-spermine/spermidine oxidase | 5 |
| 3965702 | 10.1021/jm00379a001 | Amine oxidase [flavin-containing] A | 1 |
| 3965702 | 10.1021/jm00379a001 | Diamine oxidase-like protein 2 | 1 |
Data from ChEMBL 36 via Core Engine